Evaluating Amyloid Beta (Aβ) 1-40 Degradation by Capillary Electrophoresis
Here, we describe a capillary electrophoresis method for evaluating proteolysis of the amyloid beta peptide (Aβ) 1–40. This method is suitable for kinetic studies, demands little specialized equipment, and consumes only small quantities of a commercially available substrate whose physiological accumulation is thought to underlie the development of Alzheimer’s disease.
Alper, Benjamin J. and Schmidt, Walter K., "Evaluating Amyloid Beta (Aβ) 1-40 Degradation by Capillary Electrophoresis" (2013). Chemistry Faculty Publications. Paper 19.