First and Last Name/s of Presenters

Kayla KrukFollow

Mentor/s

Dr. Jareb, Dr. Pierce

Participation Type

Paper Talk

Abstract

The organ shortage has become a prominent problem for public health as thousands of patients die per year because of the limited availability. Research has found that xenotransplantation could be the solution to this deathly public health issue. By using animal organs to transplant into humans, there would be a significant increase in availability thus saving countless lives of those in need of organs. In this article research has been done to show the barriers of xenotransplantation that cause organ failure and solutions that have been successful in overcoming those barriers. Barriers that cause organ rejection include immune rejection, inflammation, coagulative dysfunction, and cross species transmission of retroviruses. Solutions include various techniques such as CRISPR/Cas9 for gene editing. Additionally, there was research showing the extensive use xenotransplantation could have in the medical world by effectively being able to treat a wide variety of diseases such as heart failure, kidney failure, liver failure, diabetes, burns, and more. The most significant and recent research was in 2022 when the first pig heart to human xenotransplantation took place. He was able to survive for two months using a genetically altered pig heart. Research has progressed immensely and has shown promising success. This suggests that xenotransplantation has the potential to make a difference in the medical world by providing a limitless amount of animal organs to transplant to patients with diseases that require a new organ.

College and Major available

Biology, Chemistry

Location

Session M: West Campus West Building W144

Start Day/Time

4-29-2022 1:15 PM

End Day/Time

4-29-2022 2:15 PM

Students' Information

Kayla Kruk

Biology, minor in chemistry and honors

Graduation May, 2022

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Apr 29th, 1:15 PM Apr 29th, 2:15 PM

Future Research of Xenotransplantation to Improve Human Health

Session M: West Campus West Building W144

The organ shortage has become a prominent problem for public health as thousands of patients die per year because of the limited availability. Research has found that xenotransplantation could be the solution to this deathly public health issue. By using animal organs to transplant into humans, there would be a significant increase in availability thus saving countless lives of those in need of organs. In this article research has been done to show the barriers of xenotransplantation that cause organ failure and solutions that have been successful in overcoming those barriers. Barriers that cause organ rejection include immune rejection, inflammation, coagulative dysfunction, and cross species transmission of retroviruses. Solutions include various techniques such as CRISPR/Cas9 for gene editing. Additionally, there was research showing the extensive use xenotransplantation could have in the medical world by effectively being able to treat a wide variety of diseases such as heart failure, kidney failure, liver failure, diabetes, burns, and more. The most significant and recent research was in 2022 when the first pig heart to human xenotransplantation took place. He was able to survive for two months using a genetically altered pig heart. Research has progressed immensely and has shown promising success. This suggests that xenotransplantation has the potential to make a difference in the medical world by providing a limitless amount of animal organs to transplant to patients with diseases that require a new organ.

 

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