Part of the Physical Sciences and Mathematics Commons

Works by Joseph Audie in Physical Sciences and Mathematics

2020

Rigorous Computational and Experimental Investigations on MDM2/MDMX-Targeted Linear and Macrocyclic Peptides, David J. Diller, Jon Swanson, Alexander S. Bayden, Chris J. Brown, Dawn Thean, David P. Lane, Anthony W. Patridge, Tomi K. Sawyer, Joseph Audie
Joseph Audie

2019

Inhibiting IL-2 Signaling and the Regulatory T-cell Pathway Using Computationally Designed Peptides, Tammy Price-Troska, Zhi-Zhang Yang, David J. Diller, Alexander S. Bayden, Mark Jarosinski, Joseph Audie, Stephen M. Ansell
Chemistry & Physics Faculty Publications

Rigorous Computational and Experimental Investigations on MDM2/MDMX-Targeted Linear and Macrocyclic Peptides, David J. Diller, Jon Swanson, Alexander S. Bayden, Chris J. Brown, Dawn Thean, David P. Lane, Anthony W. Patridge, Tomi K. Sawyer, Joseph Audie
Chemistry & Physics Faculty Publications

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2018

Inhibiting IL-2 Signaling and the Regulatory T-cell Pathway Using Computationally Designed Peptides, Tammy Price-Troska, Zhi-Zhang Yang, David J. Diller, Alexander S. Bayden, Mark Jarosinski, Joseph Audie, Stephen M. Ansell
Joseph Audie

Drug Screening Target for Alzheimer's Disease and Method of Screening Potential Drugs, Joseph Audie, Sergei Y. Ponomarev
Joseph Audie

An Unexpected Way Forward: Towards a More Accurate and Rigorous Protein-Protein Affinity Scoring Function by Eliminating Terms from an Already Simple Scoring Function, Jon Swanson, Joseph Audie
Chemistry & Physics Faculty Publications

PeptideNavigator: An Interactive Tool for Exploring Large and Complex Data Sets Generated During Peptide-based Drug Design Projects, Kylie I. Diller, Alexander S. Bayden, Joseph Audie, David J. Diller
Chemistry & Physics Faculty Publications

2017

PeptideNavigator: An Interactive Tool for Exploring Large and Complex Data Sets Generated During Peptide-based Drug Design Projects, Kylie I. Diller, Alexander S. Bayden, Joseph Audie, David J. Diller
Joseph Audie

Efficient Synthesis of α-Fluoromethylhistidine Di-Hydrochloride and Demonstration of its Efficacy as a Glutathione S-Transferase Inhibitor, Kelly L. Considine, Lazaros Stefanidis, Karl G. Grozinger, Joseph Audie, Benjamin Alper
Joseph Audie

Efficient Synthesis of α-Fluoromethylhistidine Di-Hydrochloride and Demonstration of its Efficacy as a Glutathione S-Transferase Inhibitor, Kelly L. Considine, Lazaros Stefanidis, Karl G. Grozinger, Joseph Audie, Benjamin Alper
Benjamin Alper

Efficient synthesis of α-fluoromethylhistidine di-hydrochloride and demonstration of its efficacy as a glutathione S-transferase inhibitor., Kelly L. Considine, Lazaros Stefanidis, Karl G. Grozinger, Joseph Audie, Benjamin J. Alper
Benjamin Alper

Efficient synthesis of α-fluoromethylhistidine di-hydrochloride and demonstration of its efficacy as a glutathione S-transferase inhibitor., Kelly L. Considine, Lazaros Stefanidis, Karl G. Grozinger, Joseph Audie, Benjamin J. Alper
Joseph Audie

Efficient Synthesis of α-Fluoromethylhistidine Di-Hydrochloride and Demonstration of its Efficacy as a Glutathione S-Transferase Inhibitor, Kelly L. Considine, Lazaros Stefanidis, Karl G. Grozinger, Joseph Audie, Benjamin Alper
Chemistry & Physics Faculty Publications

An Unexpected Way Forward: Towards a More Accurate and Rigorous Protein-Protein Affinity Scoring Function by Eliminating Terms from an Already Simple Scoring Function, Jon Swanson, Joseph Audie
Joseph Audie

2016

Peptide Drug Discovery: Innovative Technologies and Transformational Medicines, David J. Diller, Mark Jarosinski, Tomi K. Sawyer, Joseph Audie
Joseph Audie

Computational Prediction and Analysis of the DR6-NAPP Interaction, Sergei Y. Ponomarev, Joseph Audie
Joseph Audie

2015

Rational, Computer-Enabled Peptide Drug Design: Principles, Methods, Applications and Future Directions, David J. Diller, Jon Swanson, Alexander S. Bayden, Mark Jarosinski, Joseph Audie
Joseph Audie

Recent Work in the Development and Application of Protein–Peptide Docking, Joseph Audie, Jon Swanson
Joseph Audie

A Combined Cheminformatic and Bioinformatic Approach to Address the Proteolytic Stability Challenge in Peptide-Based Drug Discovery, Alexander S. Bayden, Edwin F. Gomez, Joseph Audie, Dhruva K. Chakravorty, David J. Diller
Joseph Audie

Rational, Computer-Enabled Peptide Drug Design: Principles, Methods, Applications and Future Directions, David J. Diller, Jon Swanson, Alexander S. Bayden, Mark Jarosinski, Joseph Audie
Chemistry & Physics Faculty Publications

A Combined Cheminformatic and Bioinformatic Approach to Address the Proteolytic Stability Challenge in Peptide-Based Drug Discovery, Alexander S. Bayden, Edwin F. Gomez, Joseph Audie, Dhruva K. Chakravorty, David J. Diller
Chemistry & Physics Faculty Publications

Peptide Drug Discovery: Innovative Technologies and Transformational Medicines, David J. Diller, Mark Jarosinski, Tomi K. Sawyer, Joseph Audie
Chemistry & Physics Faculty Publications

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2014

Drug Screening Target for Alzheimer's Disease and Method of Screening Potential Drugs, Joseph Audie, Sergei Y. Ponomarev
Chemistry & Physics Faculty Publications

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2013

The Synergistic Use of Computation, Chemistry and Biology to Discover Novel Peptide-Based Drugs: The Time is Right, Joseph Audie, C. Boyd
Joseph Audie

Development and Validation of an Empirical Free Energy Function for Calculating Protein–Protein Binding Free Energy Surfaces, Joseph Audie
Joseph Audie

Advances in the Prediction of Protein-Peptide Binding Affinities: Implications for Peptide-Based Drug Discovery, Joseph Audie, Jon Swanson
Joseph Audie

Continued Development of an Empirical Function for Predicting and Rationalizing Protein–Protein Binding Affinities, Joseph Audie
Joseph Audie

A Novel Empirical Free Energy Function That Explains And Predicts Protein–Protein Binding Affinities, Joseph Audie, Suzanne Scarlata
Joseph Audie

Advances in the Prediction of Protein-Peptide Binding Affinities: Implications for Peptide-Based Drug Discovery, Joseph Audie, Jon Swanson
Chemistry & Physics Faculty Publications

2012

Recent Work in the Development and Application of Protein–Peptide Docking, Joseph Audie, Jon Swanson
Chemistry & Physics Faculty Publications

2011

Computational Prediction and Analysis of the DR6-NAPP Interaction, Sergei Y. Ponomarev, Joseph Audie
Chemistry & Physics Faculty Publications

2010

The Synergistic Use of Computation, Chemistry and Biology to Discover Novel Peptide-Based Drugs: The Time is Right, Joseph Audie, C. Boyd
Chemistry & Physics Faculty Publications

2009

Continued Development of an Empirical Function for Predicting and Rationalizing Protein–Protein Binding Affinities, Joseph Audie
Chemistry & Physics Faculty Publications

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Development and Validation of an Empirical Free Energy Function for Calculating Protein–Protein Binding Free Energy Surfaces, Joseph Audie
Chemistry & Physics Faculty Publications

PDF

2007

A Novel Empirical Free Energy Function That Explains And Predicts Protein–Protein Binding Affinities, Joseph Audie, Suzanne Scarlata
Chemistry & Physics Faculty Publications

PDF

Method for estimating protein-protein binding affinities, Joseph Audie
Joseph Audie

2006

Description of an Empirical Free Energy Function that Explains and Predicts Protein-ligand Binding Affinities, Joseph Audie
Joseph Audie