What is the Analgesic Ceiling Dose of Ketorolac for Treating Acute Pain in the ED?
Recent research has suggested that ketorolac has an analgesic ceiling effect, meaning that despite increased dosages, the patient obtains no additional pain relief and is more likely to suffer adverse drug reactions. This article describes the outcomes of these studies and the recommendation to use the lowest possible dose for the shortest time when treating patients with acute pain.
Jaglal, R. & Nemec, E.C. (2023). What is the analgesic ceiling dose of ketorolac for treating acute pain in the ED? JAAPA, 36(5), 43-44. Doi: 10.1097/01.JAA.0000923576.90074.2a