The Effects of a Protein and Carbohydrate Recovery Beverage on Muscle Protein Accretion in Trained Weightlifters

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Exercise Science


Human skeletal muscle expresses significant plasticity of phenotype in response to an applied stimulus. Skeletal muscle in response to a resistance training stimulus undergoes a transformative process where cellular signaling pathways lead to increases in contractile proteins that overtime express themselves in muscular hypertrophy. Diametrically opposed to these anabolic signaling pathways are the cellular survival and homeostatic regulatory pathways that are integrated with energy availability and balance. Attempting to shift the balance between the anabolic and catabolic pathways is the basis for adaptation-recovery and can be altered via training and the use of recovery methods including nutritional interventions. PURPOSE: To examine the effects of a recovery supplement containing protein and carbohydrate given immediately after each training session on muscle protein accretion in trained weightlifters. METHODS: 10 trained male weightlifters completed a 12-week training protocol implementing block periodization. A double blind placebo protocol was utilized to compare effects between treatment and placebo groups. The treatment group received a protein and carbohydrate recovery beverage and the placebo group received a calorie free beverage. Muscle biopsies were obtained pre and post the 12 week training intervention training and samples were analyzed for the specific muscle proteins (mTOR, AMPK, pmTOR, pAMPK) and gene expression of myosin heavy chains 1, 6 and 7. RESULTS: Pre and post increases were found for total mTOR (p=0.044) for the treatment group but not for pmTOR (p=0.385), AMPK (p=0.159), and pAMPK (p=0.430). No statistical difference was found pre and post for gene expression of myosin heavy chain 1 (p=0.08), 6 (p=0.08) or 7 (p=0.37) for the treatment group. CONCLUSION: These findings indicate that a protein supplementation has positive effects on total mTOR accretion and was trending towards a positive effects on myosin heavy chains 1 and 6 in trained weightlifters. This data indicates a potential acute anabolic effect from the consumption of a protein and carbohydrate recovery beverage following training in trained male weightlifters




Medicine and Science in Sports and Exercise