In-vivo confirmation of A-alpha mating-type identity predicted from genomic sequences in Schizophyllum commune
Mentor/s
Kirk Bartholomew
Participation Type
Poster
Abstract
Shizophyllum commune is a mushroom-forming fungus that has long-served as a model system for investigating the molecular control of development through study of its complex mating system. The A mating-type loci, Aα and Aβ, contribute to partial determination of self vs. non-self partners during the initial step in sexual development. The Aα locus has been extensively studied and encodes homeodomain proteins that interact to alter expression of genes required for sexual development. We have analyzed the predicted genes of the Aα locus in the genomes of two strains of S. commune of unknown mating type and formulated hypotheses concerning their mating-type identity based on comparison to previously characterized mating-type loci of known identity. The results of our in-silico analysis will be presented along with progress in confirming these predictions in vivo.
College and Major available
Biology
Location
University Commons
Start Day/Time
4-21-2017 1:00 PM
End Day/Time
4-21-2017 3:00 PM
Creative Commons License
This work is licensed under a Creative Commons Attribution-Noncommercial-Share Alike 3.0 License.
In-vivo confirmation of A-alpha mating-type identity predicted from genomic sequences in Schizophyllum commune
University Commons
Shizophyllum commune is a mushroom-forming fungus that has long-served as a model system for investigating the molecular control of development through study of its complex mating system. The A mating-type loci, Aα and Aβ, contribute to partial determination of self vs. non-self partners during the initial step in sexual development. The Aα locus has been extensively studied and encodes homeodomain proteins that interact to alter expression of genes required for sexual development. We have analyzed the predicted genes of the Aα locus in the genomes of two strains of S. commune of unknown mating type and formulated hypotheses concerning their mating-type identity based on comparison to previously characterized mating-type loci of known identity. The results of our in-silico analysis will be presented along with progress in confirming these predictions in vivo.
