Mentor/s
Professor Thomas Terleph
Participation Type
Paper Talk
Abstract
Stem cell transplants have become common treatment for certain types of cancer including multiple myeloma and acute lymphoblastic leukemia. There are two types of stem cells that are derived from different places. Autologous stem cells are taken from the body of a sick patient and put back into the same patient after treatment. Allogeneic stem cells come from a donor and are given to a person who is sick as treatment. The main focus of this paper is to analyze the two different type of stem cell treatments and to determine which one is a more effective method in treating patients with blood related cancers.
The biggest risks associated with autologous stem cell transplant are rejection of the cells and reinjecting cancer cells back into the patient if the extracted stem cells were not properly purged. The biggest risk associated with allogeneic stem cell transplant are rejection of the new stem cells and infection from them. There have been more benefits associated with allogeneic stem cells because of their ability to potentially fight off the disease. This phenomena is known as the graft vs. cancer effect, it is when the immune system cells from the donor work to kill the cancer in the recipient. The autologous stem cells can prolong someone’s life but cannot keep the cancer from coming back. Allogeneic stem cells have more risks associate with them, however the benefits outweigh the risk making this the more efficient stem cell treatment.
College and Major available
Biology
Location
Panel H: University Commons UC 105
Start Day/Time
4-20-2018 2:00 PM
End Day/Time
4-20-2018 3:00 PM
Creative Commons License
This work is licensed under a Creative Commons Attribution-Noncommercial-Share Alike 4.0 License.
Medical Advantages of Allogeneic vs Autologous Stem Cell Transplants as Treatment in Blood Related Cancer Patients
Panel H: University Commons UC 105
Stem cell transplants have become common treatment for certain types of cancer including multiple myeloma and acute lymphoblastic leukemia. There are two types of stem cells that are derived from different places. Autologous stem cells are taken from the body of a sick patient and put back into the same patient after treatment. Allogeneic stem cells come from a donor and are given to a person who is sick as treatment. The main focus of this paper is to analyze the two different type of stem cell treatments and to determine which one is a more effective method in treating patients with blood related cancers.
The biggest risks associated with autologous stem cell transplant are rejection of the cells and reinjecting cancer cells back into the patient if the extracted stem cells were not properly purged. The biggest risk associated with allogeneic stem cell transplant are rejection of the new stem cells and infection from them. There have been more benefits associated with allogeneic stem cells because of their ability to potentially fight off the disease. This phenomena is known as the graft vs. cancer effect, it is when the immune system cells from the donor work to kill the cancer in the recipient. The autologous stem cells can prolong someone’s life but cannot keep the cancer from coming back. Allogeneic stem cells have more risks associate with them, however the benefits outweigh the risk making this the more efficient stem cell treatment.
