Mentor/s
Dr. Alyssa Woronik
Participation Type
Paper Talk
Abstract
Clustered regularly interspaced short palindromic repeats (CRISPR) based gene editing has emerged as an invaluable tool for advances in human health. Through the simple design of single-guide RNAs (sgRNAs), CRISPR-associated proteins (Cas) are guided to make edits within genomes with relative ease compared to previous gene editing techniques. The development of this technology has allowed for improved treatment of diseases such as Sickle Cell Anemia and Leber Congenital Amaurosis. Its usage extends further than just disease treatments, as seen by the ability to decrease malaria transmission rates and increase nutritional value in food. Despite justifiable concerns with the possibility of CRISPR making unwanted gene edits, issues of delivery to cells, and ethical implications, the benefits of CRISPR cannot be ignored. With future work being completed in conjunction with the already known feats of the technology, CRISPR gene editing will ultimately revolutionize the landscape of human health.
College and Major available
Biology
Academic Level
Undergraduate student
Location
Session 2: Digital Commons & Martire 251
Start Day/Time
4-23-2025 2:00 PM
End Day/Time
4-23-2025 3:15 PM
Creative Commons License
This work is licensed under a Creative Commons Attribution-Noncommercial 4.0 License
CRISPR-Cas9: Will it Revolutionize the Landscape of Human Health?
Session 2: Digital Commons & Martire 251
Clustered regularly interspaced short palindromic repeats (CRISPR) based gene editing has emerged as an invaluable tool for advances in human health. Through the simple design of single-guide RNAs (sgRNAs), CRISPR-associated proteins (Cas) are guided to make edits within genomes with relative ease compared to previous gene editing techniques. The development of this technology has allowed for improved treatment of diseases such as Sickle Cell Anemia and Leber Congenital Amaurosis. Its usage extends further than just disease treatments, as seen by the ability to decrease malaria transmission rates and increase nutritional value in food. Despite justifiable concerns with the possibility of CRISPR making unwanted gene edits, issues of delivery to cells, and ethical implications, the benefits of CRISPR cannot be ignored. With future work being completed in conjunction with the already known feats of the technology, CRISPR gene editing will ultimately revolutionize the landscape of human health.
Students' Information
Biology, Honors, 2025