Mammalian DNA Mismatch Repair

Authors

Andrew B. Buermeyer, Oregon Health & Science University
Suzanne M. Deschênes, Sacred Heart UniversityFollow
Sean M. Baker, University of California - Berkeley
R. Michael Liskay, Oregon Health & Science University

Document Type

Article

Publication Date

1999

Abstract

Details the process of DNA mismatch repair in mammals (MMR). Mismatch repair in Escherichia coli and in eukaryotes; Phenotypes of MMR gene defiencies; Role of MMR genes in mouse tumorigenesis; Role of MMR genes in mutation avoidance; Other phenotypes associated with MMR gene defects; Defining the relationship between the functions of MMR in mutation and tumor avoidance.

DOI

10.1146/annurev.genet.33.1.533

Recommended Citation

Buermeyer, Andrew B., Deschênes, Suzanne M., Baker, S.M., Lisaky, R.M. "Mammalian DNA Mismatch Repair." Annual Review of Genetics 33 (1999): 553-564.