Mammalian DNA Mismatch Repair

Document Type

Article

Publication Date

1999

Abstract

Details the process of DNA mismatch repair in mammals (MMR). Mismatch repair in Escherichia coli and in eukaryotes; Phenotypes of MMR gene defiencies; Role of MMR genes in mouse tumorigenesis; Role of MMR genes in mutation avoidance; Other phenotypes associated with MMR gene defects; Defining the relationship between the functions of MMR in mutation and tumor avoidance.

DOI

10.1146/annurev.genet.33.1.533


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